Sunday 15 January 2017

NEJM Week of 22nd December 2016 (#74)

Professor Brian Andrews NEJM Recommendations for Medical Students and Tutors
Week of 22nd December 2016 (#74)
University of Notre Dame Australia (Fremantle Campus)



Occasional Editorial Comment


None



Must Read Articles


Perspective

All in a Day’s Work — Equity vs. Equality at a Public ICU in Brazil


Every day, Brazilian intensivists face cruel choices about which patients will be given the care they need. Should a 32-year-old woman with respiratory failure receive extracorporeal membrane oxygenation? Or should the money be spent instead on 1250 doses of antibiotics?



Articles Recommended for Medical Students


EDITORIAL

Acute Otitis Media — The Long and the Short of It



ORIGINAL ARTICLE

Shortened Antimicrobial Treatment for Acute Otitis Media in Young Children


In children 6 to 23 months of age with otitis media, 5 days of antibiotic therapy was associated with less-favorable outcomes than standard 10-day treatment. The shorter course did not result in a lower rate of adverse events or of emergence of antimicrobial resistance.


REVIEW ARTICLE

Neonatal Abstinence Syndrome


Infants born to mothers who take opioids may have symptoms of opioid withdrawal after birth. Early detection and holistic treatment that incorporates pharmacologic and nonpharmacologic interventions can help improve outcomes for affected infants.


IMAGES IN CLINICAL MEDICINE

Acute Rheumatic Fever with Erythema Marginatum


A 36-year-old man presented with fever and pain in both shoulders and knees, which had been preceded by a sore throat. His symptoms abated after administration of an NSAID. One week later, painless, nonpruritic, red annular macules appeared on the upper limbs and abdomen.


IMAGES IN CLINICAL MEDICINE

Uterine Rupture with Protruded Legs in a Large Amniocele


A 33-year-old woman presented at 22 weeks of gestation with a large herniation of the amniotic sac, detected by routine ultrasonography. MRI revealed a 2.5-cm rupture of the left uterine wall and a large amniocele that contained fetal legs.



CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL

Case 39-2016 — A 74-Year-Old Man with Rectal Bleeding and a History of Prostate Cancer

http://www.nejm.org/doi/full/10.1056/NEJMcpc1613458

A 74-year-old man with a history of prostate cancer presented with rectal bleeding of 6 months' duration. Examination revealed a rectal mass. A diagnostic procedure was performed, and management decisions were made.



EDITORIAL

Atrial Fibrillation and PCI — Do We Still Need Aspirin?



Important Articles Related to Mechanisms of Disease and Translational Research



CLINICAL IMPLICATIONS OF BASIC RESEARCH

Tracking the Fate of Cells in Health and Disease


A new method that involves marking DNA by changing its sequence may provide a more accurate understanding of developmental disorders and cancer in models of disease.



Other Articles which should interest medical students


ORIGINAL ARTICLE

Hypothermia for Neuroprotection in Convulsive Status Epilepticus


In patients with convulsive status epilepticus, the addition of cooling to 32 to 34°C for 24 hours did not have a significant effect on the percentage of patients with good outcomes at 90 days as compared with standard seizure treatment alone.



New Pharmacological Therapies


None



Other articles which may be of interest to certain students


None