Professor
Brian Andrews NEJM Recommendations for Medical Students and Tutors
Week
of 12th January 2017 (#77)
University
of Notre Dame Australia (Fremantle Campus)
Occasional Editorial Comment
None
Must Read Articles
CLINICAL PRACTICE
Screening
for Colorectal Neoplasia
Screening
for colorectal neoplasia should be initiated at 50 years of age, with tailored
screening between 76 and 85 years of age. Most guidelines do not specifically
recommend one screening strategy over others; this article reviews current
screening strategies.
Articles Recommended for Medical Students
Perspective
Patient-Reported
Outcomes — Harnessing Patients’ Voices to Improve Clinical Care
Recording
patient-reported outcomes electronically in real time and allowing clinicians
to review longitudinal PRO reports can improve patients' quality of life,
enhance patient–clinician communication, reduce emergency department
utilization, and lengthen survival.
ORIGINAL ARTICLE
Trial
of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine
In
childhood and adolescent migraine, amitriptyline and topiramate were no better
than placebo and not significantly different from each other in achieving a 50%
or greater reduction in days with headache. The trial was stopped early for
futility.
EDITORIAL
Pediatric
Migraine Headache — Still Searching for Effective Treatments
IMAGES IN CLINICAL MEDICINE
Circinate
Balanitis
A
37-year-old man presented with genital lesions, weight loss, and back pain,
preceded 2 months earlier by dysuria and urethral discharge that had resolved.
Examination revealed erythematous, annular plaques on the glans penis, and
meatal inflammation.
IMAGES IN CLINICAL MEDICINE
Fibromuscular
Dysplasia of the Brachial Artery
A
68-year-old woman presented with exertional dyspnea and chest pain. She had
undergone CABG 5 years earlier. Vascular examination revealed palpable radial
pulses on both sides of the body; right brachial angiography revealed a “string
of beads” pattern.
CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL
Case
1-2017 — A 70-Year-Old Woman with Gradually Progressive Loss of Language
A
70-year-old woman presented with gradually progressive aphasic impairment of
word finding, object naming, and word comprehension; other areas of cognition
were mostly intact. A clinical diagnosis was made, and additional tests were
performed.
Important Articles Related to Mechanisms of Disease and
Translational Research
CLINICAL IMPLICATIONS OF BASIC RESEARCH
Mitochondrial
Donation — Clearing the Final Regulatory Hurdle in the United Kingdom
A
study uncovers aspects of mtDNA replication in cell lines derived from early
stage embryos; meanwhile, a regulatory authority in the United Kingdom has
given the green light to “mitochondrial donation” techniques to reduce risk of
transmitting mitochondrial disorders.
Other Articles which should interest medical students
None
New Novel Therapies
None
