Professor
Brian Andrews NEJM Recommendations for Medical Students and Tutors
Week
of 24th November 2016 (#70)
University
of Notre Dame Australia (Fremantle Campus)
Occasional Editorial Comment
None
Must Read Articles
None
Articles Recommended for Medical Students
CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL
Case
36-2016 — A 50-Year-Old Man with Acute Liver Injury
A 50-year-old
man from India, with a remote history of alcohol use, was admitted to this
hospital because of abnormal liver function test results, anemia, and acute
kidney injury. A diagnosis was made.
ORIGINAL ARTICLE
BRIEF REPORT
Fully
Implanted Brain–Computer Interface in a Locked-In Patient with ALS
Electrical
signals from fully implanted surface electrodes over the cerebral motor cortex
were decoded to allow a locked-in patient with ALS to control a computer cursor
and type independently at a slow pace.
REVIEW ARTICLE
Von
Willebrand’s Disease
Von
Willebrand's disease is the most common inherited bleeding disorder and is
generally transmitted as an autosomal dominant trait. It is mainly associated
with mucosal bleeding and excessive bleeding after trauma or surgery. A variety
of effective treatments are available.
IMAGES IN CLINICAL MEDICINE
Large
Hiatal Hernia
An
81-year-old woman presented with vomiting. Chest radiography showed a large
air–liquid shadow in the inferior retrocardiac position, suggesting a
paraesophageal hernia. CT showed a large retrocardiac mass that was consistent
with herniation of the stomach into the chest.
Important Articles Related to Mechanisms of Disease and
Translational Research
CLINICAL IMPLICATIONS OF BASIC RESEARCH
BASIC IMPLICATIONS OF CLINICAL OBSERVATIONS
Nephron
Protection in Diabetic Kidney Disease
This
commentary discusses nephron protection in diabetic kidney disease and
describes the way in which renin–angiotensin system inhibitors and the
sodium–glucose cotransporter 2 inhibitor empagliflozin have renoprotective
effects.
Other Articles which should interest medical students
ORIGINAL ARTICLE
Thresholds
for Abdominal Aortic Aneurysm Repair in England and the United States
Hospital
and registry data and national statistics showed a lower rate of abdominal
aortic aneurysm repair and a larger mean aneurysm diameter at repair in England
than in the United States; U.S. rates of aneurysm rupture and aneurysm-related
death were lower.
IMAGES IN CLINICAL MEDICINE
Dizziness
and Vertigo during MRI
A
33-year-old man participating in a research study underwent MRI in a 7-tesla
MRI scanner. On entering the scanner, he had a spinning sensation for 2
minutes. Nystagmus, recorded with infrared goggles and shown in a video,
continued for the entire 90-minute scanning period.
New Pharmacological Therapies
None
Other articles which may be of interest to certain students
ORIGINAL ARTICLE
TP53 and
Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes
Decitabine
produced responses in patients with acute myeloid leukemia or myelodysplastic
syndromes who had cytogenetic abnormalities associated with a poor prognosis,
including 21 of 21 patients with tumors that contained TP53mutations.
EDITORIAL
Acute
Myeloid Leukemia — Many Diseases, Many Treatments
